Publications

  1. Megagiannis P, Mei Y, Yan RE, Yuan L, Wilde JJ, Eckersberg H, Suresh R, Tan X, Chen H, Farmer WT, Cha K, Le PU, Catoire H, Rochefort D, Kwan T, Yee BA, Dion P, Krishnaswamy A, Cloutier JF, Stifani S, Petrecca K, Yeo GW, Murai KK, Feng G, Rouleau GA, Ideker T, Sanjana NE, Zhou Y. (2024) Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes. Cell Rep. 43(8):114637. doi: 10.1016/j.celrep.2024.114637. PMID: 39154337

  2. Raja R, Dumontier E, Phen A, Cloutier JF (2024) Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development. Genesis. 62(2):e23594. doi: 10.1002/dvg.23594.PMID: 38590146

  3. Quilez S, Dumontier E, Baim C, Kam J, Cloutier JF (2024) Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects (2024) Front Cell Dev Biol. 12:1256465. doi: 10.3389/fcell.2024.1256465. eCollection 2024.PMID: 38404688

  4. Wang XF, Vigouroux R, Syonov M, Baglaenko Y, Nikolakopoulou AM, Ringuette D, Rus H, DiStefano PV, Dufour S, Shabanzadeh AP, Lee S, Mueller BK, Charish J, Harada H, Fish JE, Wither J, Wälchli T, Cloutier JF, Zlokovic BV, Carlen PL, Monnier PP. (2024) The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity. Nat Commun. 15(1):1037. doi: 10.1038/s41467-024-45303-1.PMID: 38310100

  5. Liakath-Ali K, Polepalli JS, Lee SJ, Cloutier JF, Südhof TC. (2022) Transsynaptic cerebellin4-neogenin1 signaling mediates LTP in the mouse dentate gyrus. Proc Natl Acad Sci U S A. 119(20):e2123421119. doi: 10.1073/pnas.2123421119.

  6. Wang, J., Vaddadi, N., Pak, J.S., Park, Y., Quilez, S., Roman, C.A., Dumontier, E., Thornton, J.W., Cloutier, J.-F., Özkan, E. (2021). Molecular and Structural Basis of Olfactory Sensory Neuron Coalescence by Kirrel Receptors. Cell Reports (37) 5: 109940.

  7. Fearnley, S., Raja, R, Cloutier, J-F. (2021). Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Scientific Reports 11 (1):19536.

  8. Bahreini JS, Lin JM, Etaati F, Fearnley S, Cloutier JF, Khmaladze A, Forni PE. (2021) Automated quantification of vomeronasal glomeruli number, size, and color composition after immunofluorescent staining. Chem Senses. Jan 1;46:bjab039. doi: 10.1093/chemse/bjab039.

  9. Brignani S, Raj DDA, Schmidt ERE, Düdükcü Ö, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, *Dumontier E, *Cloutier JF, Chédotal A, Pasterkamp RJ. (2020). Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 107: 684-702.

  10. Hassani, OK, Rymar, VV, Nguyen, KQ, Huo, L, Cloutier, JF, Miller, FD, Sadikot, AF. (2020). The noradrenergic system is necessary for survival of vulnerable midbrain dopaminergic neurons: implications for development and Parkinson's disease.Neurobiol Aging. 85: 22-37.

  11. Luo L, Ambrozkiewicz MC, Benseler F, Chen C, *Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, Motohashi J, Pai EL, Pelkey KA, Pereira A, Philips T, Sinclair JL, Stogsdill JA, Traunmüller L, Wang J, Wortel J, You W, Abumaria N, Beier KT, Brose N, Burgess HA, Cepko CL, *Cloutier JF, Eroglu C, Goebbels S, Kaeser PS, Kay JN, Lu W, Luo L, Mandai K, McBain CJ, Nave KA, Prado MAM, Prado VF, Rothstein J, Rubenstein JLR, Saher G, Sakimura K, Sanes JR, Scheiffele P, Takai Y, Umemori H, Verhage M, Yuzaki M, Zoghbi HY, Kawabe H, Craig AM. (2020). Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron. 106: 37-65.

  12. Harada, H, Farhani, N, Wang, X.F., Sugita, S, Charish, J, Attisano, L, Moran, M, Cloutier, J.-F., Reber, M, Bremner, R, Monnier, P.P. (2019). Extracellular phosphorylation drives the formation of neuronal circuitry. Nat Chem Biol. 15: 1035-1042.

  13. Vaddadi, N, Iversen, K, Raja, R, Phen, A, Brignall, A, Dumontier, E and Cloutier, J-F. (2019). Kirrel2 is differentially required in populations of olfactory sensory neurons for the targeting of axons in the olfactory bulb. Development. 146: dev173310.

  14. Brignall, A.C., Raja, R., Phen, A., Prince, J.E.A, and Cloutier, J.-F. (2018). Loss of Kirrel family members alters glomerular structure and synapse numbers in the accessory olfactory bulb. Brain Structure and Function. 223: 307-319.

  15. Sanz RL, Ferraro GB, Kacervosky J, Salesse C, Gowing E, Hua L, Rambaldi I, *Beaubien F, Holmbeck K, Cloutier JF, Lévesque M, Murai K, Fournier AE. (2018). MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding.Journal of Neuroscience. 17: 519-529.

  16. Yung AR, Druckenbrod NR, Cloutier J.-F., Wu Z, Tessier-Lavigne M, Goodrich LV. (2018). Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS.Cell Reports. 13: 1666-1680.

  17. Beaubien, F., Raja, R., Kennedy, T., Fournier. A.E., Cloutier, J.-F. (2016). Slitrk1 is localized to excitatory synapses and promotes their development.Scientific Reports. 6: 27343.

  18. Kam, J.W.K., Dumontier, E., Brignall, A.C., Mendes da Silva, D., Cowan, M., Kennedy, T.E., Cloutier, J.-F. (2016) RGMB and Neogenin control progenitor cell differentiation in the developing olfactory epithelium Development 143: 1534-46.

  19. Beaubien, F., Raja, R., Kennedy, T., Cloutier, J.-F. (2016) Slitrk1 is localized to excitatory synapses and promotes their development. Sci. Rep. 6:27343.

  20. Brignall, A.C., Cloutier, J.F. (2015) Neural map formation and sensory coding in the vomeronasal system. Cell Mol Life Sci. 72:4697-709.

  21. Poliak, S., Kao, T.J., Krawchuck, D., Croteau, L.-P., Palmesino, E., Morton, S., Cloutier, J-F, Charron, F., Ackerman, S., Kania, A. (2015) Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. Elife 4:e10841.

  22. Bin, J.M., Han, D., Lai Wing Sun, K., Croteau, L.P., Dumontier, E., Cloutier, J.F., Kania, A., Kennedy, T.E. (2015) Complete loss of netrin-1 results in embryonic lethality and severe axon guidance defects without increased neural cell death. Cell Rep. 12:1099-106.

  23. Khazaei, M.R., Girouard, M.P., Alchini, R., Ong Tone, S., Bechstedt, S., Cowan, M., Guillet, D., Wiseman, P., Brouhard, G., Cloutier, J.F., Fournier, A.E. (2014) Collapsin Response Mediator Protein 4 regulatse growth cone dynamics through the actin microtubule sytoskeleton. J. Biol. Chem. 289: 30133-43.

  24. Kam, J.W., Raja, R., Cloutier, J.-F. (2014) Cellular and molecular mechanisms regulating embryonic neurogenesis in the olfactory epithelium. Int. J. Dev. Neurosci. 37:76-86.

  25. Prince, J.H., Brignall, A.C., Cutforth, T., Shen, K., Cloutier, J.-F. (2013) Kirrel-3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression. Development 140: 2398-2408.

  26. Samadi, P., Boutet, A., Rymar, V.V., Rawal, K., Maheux, J., Kvann, J.C., Tomaszewski, M., Beubien, F., Cloutier, J.-F., Levesque, D., Sadikot, A.F. (2013) Relationship between BDNF expression in major afferents, striatum morphology and motor behavior in the R6/2 mouse model of Huntington’s disease. Genes Brain Behav. 12: 108-124.

  27. Cho, J.H., Kam, J.W., Cloutier, J.-F. (2012) Slits and Robo-2 regulate the coalescence of subsets of olfactory sensory neuron axons within the ventral region of the olfactory bulb. Dev. Biol. 15;371:269-79.

  28. Cho, J.H., Prince, J.E.A, Cutforth, T., Cloutier, J.-F. (2011) The pattern of glomerular map formation defines responsiveness to aversive odorants. J. Neurosci. 31:7920-7926.

  29. Phan K.D., Croteau, L.P., Kam J. W., Kania A, Cloutier, J.-F., Butler, S.J. (2011) Neogenin may functionally substitute for DCC in chicken. PLoS One 6(7):e22072.

  30. Hernandez-Miranda, L., Cariboni, A. Faux, C., Ruhrberg, C., Cho, J.H., Cloutier, J.-F., Eickholt, B., Parnavelas, J.G., Andrews, W. (2011) Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain. J. Neurosci. 31:6174-6187.

  31. Beaubien, F., Prince, J.E.A., Cloutier, J.-F. Axon Guidance: Slit-Robo signaling. In: Comprehensive Developmental Neuroscience, Elsevier. in press.

  32. Prince, J. E. A., Cho, J.H., Dumontier, E., Cho, J.H., Andrews W., Cutforth, T., Tessier-Lavigne, M., Parnavelas, J., Cloutier, J.-F. (2009) Robo-2 controls the segregation of subsets of basal vomeronasal sensory neuron axons to the posterior accessory olfactory bulb throughout development. J. Neurosci. 29:14211-22.

  33. Beaubien, F. and Cloutier, J.-F. (2009) Differential expression of Slitrk family members in the mouse nervous system. Dev. Dyn. 238:3285-96.

  34. Cho, J.H., Prince, J., Cloutier, J.-F. (2009) Axon guidance events in the wiring of the mammalian olfactory system. Mol. Neurobiol. 39:1-9.

  35. Briançon-Marjollet A, Ghogha A, Nawabi H, Triki I, Auziol C, Fromont S, Piché C, Enslen H, Chebli K, Cloutier JF, Castellani V, Debant A, Lamarche-Vane N. (2008) Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance. Mol. Cell. Biol. 28: 2314-2323.

  36. Cho, J.H., Lépine, M., Andrews, W., Parnavelas, J., Cloutier, J.-F. (2007) Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb. J. Neurosci. 27: 9094-10004.

  37. Cloutier, J.-F. Odorant Receptors: Genomics. In: Binder M, Hirokawa, N., Windhorst, U. (Eds) Encyclopedia of Neuroscience. Springer.